Evidence for a weak angiogenic response to human colorectal cancers.

and (iii) fibroblast-like cells. Vascular density of carcinomas compared with normal mucosa The mean vascular circumference in normal mucosa was lower than in either central or peripheral regions of both moderately and poorly differentiated carcinomas (Table I). These differences were all highly significant (P<0.O01).

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These differences were significant for Sv and Lv (P=0.014 and 0.030 respec- tively), and marginally significant for Vv (P=0.059).

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