Recently, Larramendy et al (1997) reported infre- quent gain of 1q material in malignant fibrous histiocytomas (MFHs), but with a more distal minimal common region, 1q24. It might be significant that many of the tumours with amplifica- tions of 1q are well-differentiated liposarcomas (WDLPS) and MFHs tumours that are often characterized by giant marker chro- mosomes containing amplified segments from various chromo- somes (Heim et al, 1987; Orndal et al, 1992; Dal Cin et al, 1993; Pedeutour et al, 1993; Nilbert et al, 1994).
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Molecular characterization of a novel amplicon at 1q21-q22 frequently observed in human sarcomas.
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