Long-term clinical protection from falciparum malaria is strongly associated with IgG3 antibodies to merozoite surface protein 3.

PLoS Med · 2007 · PMC2071934 · PMID 18001147

Europe PMC DOI

hedged sentences

0.0400

closest p · 0.8× alpha

0.0400

boldest claim

The sentences

marginally significantp = 0.04actually significant

MSP1 IgG4 and AMA1 IgG3 were marginally significant if tested separately ( p = 0.04 and 0.05 respectively), but were not significant if included in a model with MSP3 IgG3.

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highly significantno p-value reported

Discussion A detailed analysis of the malarial clinical status, based on daily medical records actively collected from each inhabitant of Dielmo, Senegal, demonstrated a highly significant relationship between clinical protection acquired through natural exposure and the production of cytophilic anti-MSP-3 antibodies, notably IgG3.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.