Radiobiology of the C3H mouse mammary carcinoma: increased radiosensitivity of the tumour induced by inoculation of the host with radiation-attenuated isografts.

The greater proportion of cures occured when the interval between the attenuated inoculum and the treatment in situ of the unmodified tumour was in the region of 4 to 5 weeks, the effective period apparently being not less than 2 weeks and continuing up to about 7 weeks. Comparing the 3-month result for this whole experimental series (26/123) cures with the observed control series treated at the same dose (0/97 cures) indicates a highly significant increased radiocurability at the probability level p < 0.00001.

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