The angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase is up-regulated in breast cancer epithelium and endothelium.

interleukin 4, data not shown) would be unable to use these networks, which would also account for the low levels of TP observed in high-grade tumours. Although no significant reduction in relapse-free survival or overall survival was observed in all patients or the node- negative subgroup, there was a significantly higher relapse- free survival and borderline significance for overall survival in node-positive patients with TP-positive tumours.

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