DNA damage following combination of radiation with the bioreductive drug AQ4N: possible selective toxicity to oxic and hypoxic tumour cells.

Br J Cancer · 1996 · PMC2074454 · PMID 8595165

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highly significantno p-value reported

These interact electrostatically with DNA, resulting in a highly significant level of AQ4 binding (Patterson, 1993) and account for several distinct differences in the properties of AQ4 as compared with AQ4N (Table I).

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