An influence of VP16 on the DNA-adduct formation could not be tested directly, because the two subgroups did receive a different dose of cisplatin. Logistic regression analysis Logistic regression analysis revealed highly significant sigmoid relationships between AUC, AUA and Am., and the likelihood of a response.
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Relationship between the exposure to cisplatin, DNA-adduct formation in leucocytes and tumour response in patients with solid tumours.
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