Transforming growth factor beta 1 expression in human colorectal tumours: an independent prognostic marker in a subgroup of poor prognosis patients.

In the patients considered to have had curative resections, the 3 year survival rate was 95% for the 13 patients with TGF-,B1- negative tumours, although there was no significant difference between these and the 18 patients with TGF-fll-positive tumours, whose 3 year survival rate was 75% (Figure 3b). There was, however, a highly significant survival advantage for patients with TGF-f1l-negative tumours within the Figure 1 Immunohistochemical staining of LAP-TGF-,B1 in a colorectal tumour specimen.

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