Barely Significant
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Isolation of rat liver plasma membranes. Use of nucleotide pyrophosphatase and phosphodiesterase I as marker enzymes.

J Cell Biol · 1970 · PMC2108168 · PMID 5497542

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highly significantno p-value reported
(3) made the highly significant observation that the specific activity of NAD pyrophosphatase is higher in plasma membranes than in microsomes.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.