This supposed lack of cation speci- ficity would be similar to that described for the behavior of kidney cortex slices swollen in salts of various cations (27). Although the activation of the ouabain-sensitive Na+,K+- ATPase by colchicine did not prove to be essential for the volume change, the activation was nonetheless statistically highly significant and thus represents a novel effect of an antimicrotubule agent on membrane function .
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Control of cell volume in the J774 macrophage by microtubule disassembly and cyclic AMP.
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