However, in every single set of experi- ments, a very similar and highly significant difference in the secretion half-times between wild-type and mutant YP2 was observed, which ranged from 16-18 min (compare Fig. 3, B and B' with Fig. 5 A).
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Inhibition of tyrosine sulfation in the trans-Golgi retards the transport of a constitutively secreted protein to the cell surface.
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