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STUDIES IN ISOAGGLUTINATION : I. TRANSFUSION AND THE QUESTION OF INTRAVASCULAR AGGLUTINATION.

J Exp Med · 1911 · PMC2124873 · PMID 19867425

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extremely significantno p-value reported
This was particularly true of the first five mixtures in the series; in the other mixtures the absorption of agglutinin by the excess of agglutinable cells present also played a part; and in the last two, they apparently prevented agglutination, as in the experiments referred to in table II. This, of course, is extremely significant for transfusion; a few large clumps might cause serious or fatal embolism.

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