Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E)

J Cell Biol · 1997 · PMC2134292 · PMID 9024700

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highly significantno p-value reported

Lowering shear resulted in a highly significant reduction of Jurkat T lymphocyte rolling within 1 s, suggesting that the change in binding to PNAd can be altered on very short time scales relative to many intracellular signaling processes.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.