Gene-interleaving patterns of synteny in the Saccharomyces cerevisiae genome: are they proof of an ancient genome duplication event?

Biol Direct · 2007 · PMC2134927 · PMID 17894859

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantP = 10 -113actually significant

What the reviewer fails to mention is that because 32% of genes do change orientation and given a sample size that will make expectations highly significant, the null hypothesis of no change will be rejected by a more significant P value (P = 10 -113 ) by Fisher test, therefore rejecting the WGD model .

also in 60,174 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.