The Per2 negative feedback loop sets the period in the mammalian circadian clock mechanism.

PLoS Comput Biol · 2007 · PMC2134962 · PMID 18085817

Europe PMC DOI

hedged sentence

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closest p

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boldest claim

The sentences

highly significantno p-value reported

Differences Between the Per1 and Per2 Loops Although Per1 and Per2 carry out similar reactions, only Per2 is singled out as highly significant in affecting the period of oscillation.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.