THE EFFECT OF HYPERGLYCEMIA ON HYPOTHALAMIC GOLD UPTAKE AND HYPERPHAGIA IN GOLDTHIOGLUCOSE-TREATED MICE.

This suggests that regions in the hypothalamus are more susceptible to damage by goldthioglucose than other brain areas. The findings that low levels of blood goldthioglucose concentration produced small focal lesions in the ventromedial area whereas higher levels of blood goldthioglucose concentration produced broader lesions of similar density suggest that there may be significant differences in the metabolism and/or supply of goldthioglucose to various regions of the ventromedial hypothalamic area.

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