Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures.

Tyrosine phosphorylation density scans were obtained for six of the experiments and revealed that 1-min application of NGF to distal axons resulted in a 2.4-fold increase in trk phosphorylation density in the cell bodies/proximal axons, which was highly significant ( P < 0.004) (Fig. 6 ).

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