Independent prognostic importance of microvessel density in endometrial carcinoma.

- mation about prognostic factors, such as disease stage, histological type and histological grade (Abler and Kj0rstad, 1991; Rose, 1996). These factors have been extensively studied (Mikuta, 1993), and our present findings generally support the view that FIGO stage, as revised in 1988, is a highly significant prognosticator.

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We found a signif- icant prognostic influence of nuclear p53 protein expression when only tumour variables were investigated, whereas p53 staining showed a borderline significance in the multivariate analysis with FIGO stage included.

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