Data from approximately 30 000 women in 40 of the trials Received 13 October 1997 Revised 18 November 1997 Accepted 18 November 1997 Correspondence to: M Clarke that began before 1985 were collected and reanalysed by the Early Breast Cancer Trialists' Collaborative Group (EBCTCG) in 1992 to reveal a small, but highly significant, reduction in 10-year mortality for women allocated to tamoxifen (EBCTCG, 1992).
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