Barely Significant
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Responses of rat P2X2 receptors to ultrashort pulses of ATP provide insights into ATP binding and channel gating.

J Gen Physiol · 2007 · PMC2151634 · PMID 17664346

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highly significantno p-value reported
In Scheme 4, there is highly significant cooperativity between each binding step, while in Schemes 6 and 7, there is negligible cooperativity of binding.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.