Trials stopped early for benefit? Not so fast!

Crit Care · 2007 · PMC2151876 · PMID 17338836

Europe PMC DOI

hedged sentence

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closest p

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boldest claim

The sentences

highly significantno p-value reported

Because the decision to stop is typically driven by highly significant p value thresholds, trials stopped early because of apparent benefit frequently show large treatment effects.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.