It should also be noted that genes with nonimmune functions such as HMG17 (coding a chromosomal protein), ABC2 (transporter protein), and NOTCH1 (signaling receptor) show the most highly significant associations of all genes tested with PML bodies ( Luciani et al., 1994 ; Artavanis-Tsakonas et al., 1995 ; Bustin et al., 1995 ).
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Promyelocytic leukemia nuclear bodies associate with transcriptionally active genomic regions.
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