Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress.

J Cell Biol · 2002 · PMC2173473 · PMID 11901170

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may be significantno p-value reported

The data suggests a linkage between tau and APP trafficking, which may be significant in Alzheimer's disease.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.