Barely Significant
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Dynactin is required for microtubule anchoring at centrosomes.

J Cell Biol · 1999 · PMC2174233 · PMID 10525538

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likely to be significantno p-value reported
The forces exerted on dynactin at centrosomes are likely to be significant since they involve large numbers of motor molecules operating on the entire microtubule cytoskeleton.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.