100 rads was chosen as a radiation dose with comparatively little harmful effects on the immune capacity of the lymphoid tissue of the recipient (10) but a dose that would allow a highly significant increase in take of transferred syngeneic lymphoid cell (11).
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Induction of specific immune unresponsiveness with purified mixed leukocyte culture-activated T lymphoblasts as autoimmunogen. III. Proof for the existence of autoanti-idiotypic killer T cells and transfer of suppression to normal syngeneic recipients by T or B lymphocytes.
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