Heterogeneity of tumorigenicity phenotype in murine tumors. I. Characterization of regressor and progressor clones isolated from a nonmutagenized ultraviolet regressor tumor.

Using this assay, the parent tumor and all clones were susceptible to lysis to the same degree, again suggesting the presence of a similar target determinant on all clones, which is recognized by CTL with functional specificity for C1 8 only (Table I). Epitope density was also considered to be a possibly significant parameter for discrimination between regressor and progressor clones.

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