albus or group C streptococcal phage-associated lysin directly into a cell wall injection site in rabbit skin results in a decrease in the severity and duration of dermal lesions (27). The demonstration that mutanolysin has a profound effect in vivo on PG-APS- induced arthritis may be significant for the study of inflammation, since it provides a unique situation in which the phlogistic agent can be rapidly and specifically inactivated in vivo while the inflammatory response is evolving.
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Treatment of experimental erosive arthritis in rats by injection of the muralytic enzyme mutanolysin.
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