Crosslinking of surface immunoglobulin and Fc receptors on B lymphocytes inhibits stimulation of inositol phospholipid breakdown via the antigen receptors.

However, at later time points, inositol phosphates levels in cells incubated with F(ab')2 antMg were higher than in those incubated with intact antibodies, and after 4 min the differences had become highly significant (p < 0.02).

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