2, the differencein magnitude of the FI B-cell response to DNP-GL@ compared to that observed with 5R B cells was highly significant (P --- 0.0032) and cannot be attributed to a lower general responsiveness on the part of F1 B cells, since the magnitude of cooperative responses of 5R and (B6A)F~ B cells with F~ KLH-specific T cells to DNP-KLH were quite comparable (cf.
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Control of t-lymphocyte and B-lymphocyte activation by two complementing Ir-GLphi immune response genes.
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