It may be significant that this/r- like gene for cytotoxic function appears to map within a region that controls those cell surface products which are associated with the antigens recognized for cytotoxic function.
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Multiple H-2 linked immune response gene control of H-2 D-associated T-cell-mediated lympholysis to trinitrophenyl-modified autologous cells: Ir-like genes mapping to the left of I-A and within the I region.
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