Identification of tyrosinase-related protein 2 as a tumor rejection antigen for the B16 melanoma.

A highly significant therapeutic effect was seen ( P <0.001) with cultures from normal or B16-immunized mice when stimulated with TRP-2 181–188 , but not with ova 257–264 peptide (when compared to treatment with IL-2 alone) (Fig. 4 ).

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