borderline significantP = 0.06
The changes in BMD in the subgroups (according to disease duration) were all significant except for the DXA-BMD hand patients with disease duration longer than 3 years ( P = 0.26) and the DXA-BMD spine ( P = 0.60) and DXA-BMD total hip patients with disease duration less than 3 years (borderline significant, P = 0.06).