T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation.

The difference between mutants and controls was highly significant (P < 0.01 for 24, 48, and 96 h; P = 0.02 for 72 h; the standard deviation observed was most likely due to mixed genetic backgrounds).

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