In the thymus of H-2 d Ly-49A transgenic mice, the skewing towards Vβ8.2 and Vα14 in NK1.1 + T cells was reduced compared with littermate controls, but still highly significant when compared with conventional (NK1.1 − ) T cells (Fig. 3 B ).
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Developmentally regulated extinction of Ly-49 receptor expression permits maturation and selection of NK1.1+ T cells.
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