Immunization of mice with urease vaccine affords protection against Helicobacter pylori infection in the absence of antibodies and is mediated by MHC class II-restricted responses.

J Exp Med · 1998 · PMC2212427 · PMID 9858514

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did not achieve significanceP < 0.05actually significant

β 2 m (−/−) knockout mice had reduced CD8 + and CD103 + cells in the gastric mucosa after oral immunization with urease plus LT relative to wild-type mice ( P < 0.05, except CD8 + cells did not achieve significance).

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