A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity.

Arthritis Res Ther · 2007 · PMC2212587 · PMID 17897462

Europe PMC DOI

hedged sentences

0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

borderline significantP = 0.055so close (0.05 < p ≤ 0.1)

The block containing rs729749 is borderline significant in the nonstratified analysis ( P = 0.055), but excluding rs2284027 and rs17811059 yields a significant association (empirical P = 0.04 in all and 0.03 in men; Table 5 ).

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highly significantno p-value reported

Stratification based on autoantibody status reveals a highly significant association of rs729749 with rheumatoid factor negative rheumatoid arthritis in men Because RA is a heterogeneous disease, it is likely that the disease contributing genes differ in different subgroups of patients.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.