Barely Significant
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Acute ENaC stimulation by cAMP in a kidney cell line is mediated by exocytic insertion from a recycling channel pool.

J Gen Physiol · 2005 · PMC2217480 · PMID 15623897

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highly significantno p-value reported
Thus, although the contribution of ENaC synthesis to individual I SC responses is minor relative to the recycling pathway, it becomes highly significant when there is multiple repetitive turnover of the apical pool.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.