Barely Significant
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The pheromone-induced nuclear accumulation of the Fus3 MAPK in yeast depends on its phosphorylation state and on Dig1 and Dig2.

BMC Cell Biol · 2007 · PMC2219999 · PMID 17963515

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Indeed, deletion of DIG2 lessened the effect of Ste12 overexpression on Fus3 localization, although the difference between the RNCF data sets was not quite statistically significant (data not shown).

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