Crystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferase.

BMC Struct Biol · 2007 · PMC2228302 · PMID 17894860

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closest p

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may be significantno p-value reported

cruzi and human HGPRT with HPP (7-hydroxy-pyrazolo [4,3-D]pyrimidine, a compound similar to allopurinol) bound to the active site [ 11 , 13 ], subtle differences were observed in the binding that may be significant for novel compound design [ 13 ].

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