Synergistic activation of ENaC by three membrane-bound channel-activating serine proteases (mCAP1, mCAP2, and mCAP3) and serum- and glucocorticoid-regulated kinase (Sgk1) in Xenopus Oocytes.

J Gen Physiol · 2002 · PMC2234457 · PMID 12149280

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highly significantP < 0.001actually significant

Thus, the data indicate a strong and highly significant (P < 0.001) potentiation between mCAP1 and Sgk1 for the I Na effect, whereas the synergism for the N effect was small (though significant) and less than additive.

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