Modeling an evolutionary conserved circadian cis-element.

PLoS Comput Biol · 2008 · PMC2242825 · PMID 18282089

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We show that highly induced genes in the GR-CLK experiment are significantly enriched in high scoring hits from the sequence model, so that we can identify a set of ∼30 genes among the top 57 induced genes which show highly significant 2- to 6-fold enrichment in sequence specificity ( Figure 3 A and Table S1 ).

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