Recombination-mediated genetic engineering of a bacterial artificial chromosome clone of modified vaccinia virus Ankara (MVA).

described a small non-significant effect of B15R deletion, very similar to that shown in Figure 3 for the E3 epitope, and with an identical p-value by t -test (p = 0.07); however, in the memory phase six months post-vaccination, they observed a highly significant ∼4.5-fold increase in CD8 + T cell response to the B15R deletion mutant.

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