Pooled data showed a highly significant reduction of the risk of colonisation for both prophylactic therapies (SAP studies: pooled OR 0.38, 95% CI 0.20 to 0.70, NNT 5; SDD studies: pooled OR 0.12, 95% CI 0.05 to 0.29, NNT 3) (Figure 2 ).
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Single-drug therapy or selective decontamination of the digestive tract as antifungal prophylaxis in critically ill patients: a systematic review.
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