marginally significantP<0.05
This gives a total of 290 cancers to 336 operations for benign lesions - a malignant to benign operation ratio of 1:1.2. Prognostic factors of cancers detected There is no significant difference between the study and historical control groups in the numbers of in situ carcinomas - 4% in the study group and 3% in the historical control, but there is a marginally significant difference (P<0.05) in the rate of advanced disease - 18% and 13% respectively.