West Midlands Oncology Association trials of adjuvant chemotherapy in operable breast cancer: results after a median follow-up of 7 years. I. Patients with involved axillary lymph nodes.

Br J Cancer · 1989 · PMC2247250 · PMID 2690913

Europe PMC DOI

hedged sentences

0.0030

closest p · 0.1× alpha

0.0600

boldest claim

The sentences

highly significantP = 0.003actually significant

borderline significanceP = 0.07so close (0.05 < p ≤ 0.1)

AVCMF (181/276 relapsed; control (199/263 relapsed); X2, = 11.68; P= 0.006. Prolongation of relapse-free survival was highly significant in premenopausal patients (X2i = 8.8; P = 0.003: Figure 2a) but of only borderline significance in post-menopausal patients (X21 = 3.3; P = 0.07: Figure 2b).

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just failed to reach significanceP = 0.06so close (0.05 < p ≤ 0.1)

When all patients were analysed, there was significant prolongation of relapse-free survival in patients with ER positive (RI = 44%; OR = 28%) and ER negative tumours (RI = 47%; OR = 37%) (Table II). There was a highly significant prolongation of relapse-free survival in patients with PR positive tumours (RI = 68%; OR= 41%; X2i= 7.8; P =0.005); the effect in patients with PR negative tumours just failed to reach significance, (RI = 68%; OR = 32% X21 = 3.4; P = 0.06), but the numbers in this group were smaller.

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