COX-2 and PPARgamma expression are potential markers of recurrence risk in mammary duct carcinoma in-situ.

BMC Cancer · 2008 · PMC2254431 · PMID 18237383

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp < 0.00001actually significant

Interestingly, expression was limited to grade 2 and 3 DCIS with a highly significant interaction (p < 0.00001) between PPARγ and grade.

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of borderline significanceno p-value reported

In a multivariate model which included size, grade, COX-2 and PPARγ positivity, we found COX-2 positivity to be a strong independent risk factor for recurrence (OR 7.90, 95% CI 1.72–36.23)., whereas size and grade were of borderline significance.

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