The Functions of PPARs in Aging and Longevity.

PPAR Res · 2007 · PMC2254525 · PMID 18317516

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of borderline significanceno p-value reported

In addition, very recent meta-analysis, paradoxically, showed a significant increase in the risk of myocardial infarction and an increase in cardiovascular death of borderline significance with rosiglitazone, a member of PPAR γ agonists that is widely used as antidiabetic agent [ 49 ].

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