Circulating matrix metalloproteinase-9 is associated with cardiovascular risk factors in a middle-aged normal population.

Multivariate regression models adjusting for age, sex and variables with highly significant associations to MMP-9 in univariate analyses (p<0.001) were performed in addition. 3) Both the total risk load model and the regression models on single risk factors were performed with and without adjustment for CRP.

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Further, the only variables that did not reach significance or close to significance when adjusting for age and sex were total cholesterol, LDL, LDL/HDL ratio and diabetes.

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