borderline significantP = 0.06
Our previous study on risk of lung cancer found a borderline significant interaction (P = 0.06) between high smoking intensity (>20 g tobacco/day) and the haplotype related with risk of lung cancer, with a 2.03-fold increased risk of lung cancer per additional 5 g tobacco/day among women carrying the haplotype, while no association were observed among female non-carriers of the haplotype with a similar smoking intensity [ 4 ].