Strikingly, although IL-13 blockade had a highly significant anti-fibrotic effect in WT mice, CAT2 −/− mice were unresponsive.
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Cationic amino acid transporter-2 regulates immunity by modulating arginase activity.
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Strikingly, although IL-13 blockade had a highly significant anti-fibrotic effect in WT mice, CAT2 −/− mice were unresponsive.